2011年的最后一期NEJM!12月29日365卷第26期的这期新鲜NEJM,颇为给力!你绝对不能错过!
【原始论文】
1. 高危患者髋关节术后的自由或限制性输血
Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery
[评论] 聚焦输血阈值
Transfusion Thresholds in FOCUS
2. 低分子肝素和危重患者的死亡率
Low-Molecular-Weight Heparin and Mortality in Acutely Ill Medical Patients
3. 贝伐单抗对卵巢癌的首次治疗
Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer
4. 贝伐单抗治疗卵巢癌的3期试验
A Phase 3 Trial of Bevacizumab in Ovarian Cancer
5. **慢性淋巴细胞白血病的_SF3B1_和其他新的癌基因**
SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
[评论] 癌症中的RNA剪接机制的突变
Mutations in RNA Splicing Machinery in Human Cancers
6. 简报:3例完整面部移植的患者
Three Patients with Full Facial Transplantation
【综述】
发病机制:在健康与疾病中的前蛋白转化酶
Mechanisms of Disease: Proprotein Convertases in Health and Disease
【MGH病例报道】
52岁男性出现乏力、感染与肾上腺增大
A 52-Year-Old Man with Weakness, Infections, and Enlarged Adrenal Glands
【基础研究的临床意义】
糖尿病干细胞的“移动病”
Diabetic Stem-Cell “Mobilopathy”
【观察】
1. 临床的版权与开放获取
Copyright and Open Access at the Bedside(免费全文)
2. 少有人走的路
【临床图片】
1. A Head Shot (免费全文)
2. Lichtenberg Figures(免费全文)