在八爪,文献还可以这样读!9月29日365卷第13期的这期NEJM,你不能错过的医学前沿进展!

【原始论文】

1. _GLCCI1_与激素治疗哮喘反应之间的基因关联

Genomewide Association between GLCCI1 and Response to Glucocorticoid Therapy in Asthma 

[评论] 走向个性化哮喘治疗的一步

A Step toward Personalized Asthma Treatment

2. COPD患者FEV1随时间的变化

Changes in Forced Expiratory Volume in 1 Second over Time in COPD

[评论] COPD肺功能的可变损耗

Variable Loss of Lung Function in COPD

3. 金雀花碱用于戒烟的安慰剂对照试验

Placebo-Controlled Trial of Cytisine for Smoking Cessation

4. 静脉注射免疫球蛋白治疗新生儿败血症

Treatment of Neonatal Sepsis with Intravenous Immune Globulin

【特别论文】

养老院居民的生活转变与认知问题

End-of-Life Transitions among Nursing Home Residents with Cognitive Issues

【临床实践】

治疗吸烟者

Treating Smokers in the Health Care Setting

【MGH病例报道】

62岁女性出现肾功能衰竭

Case 30-2011 — A 62-Year-Old Woman with Renal Failure

【观察】

1. 减少疗养院不必要的住院

Reducing Unnecessary Hospitalizations of Nursing Home Residents

2. 谁拥有联邦政府资助的研究?最高法院和拜杜法案

Who Owns Federally Funded Research? The Supreme Court and the Bayh–Dole Act

3. 为贫困者服务

Providing for Those Who Have Too Little

4. “百万心脏”的倡议 – 防止心脏病发作和中风

The “Million Hearts” Initiative — Preventing Heart Attacks and Strokes

【医疗法律、伦理和人权】

限制处方数据用于新药推广

Restrictions on the Use of Prescribing Data for Drug Promotion

【临床图片】

1. 上颌窦异位牙 Ectopic Tooth in the Maxillary Sinus

2. 眼和脑动静脉畸形 Orbital and Cerebral Arteriovenous Malformations